Synthesis and Study of Stabilization of Selenium Nanoparticles in the Medium of Water-Soluble Nonionic Surfactants

Abstract

This paper is aimed at synthesizing and studying the stabilization of selenium nanoparticles in a medium of water-soluble nonionic surfactants. Selenium nanoparticles were obtained by chemical reduction in an aqueous medium. Selenous acid was used as a selenium-containing precursor, nonionic surfactants were stabilizers, and ascorbic acid acted as a reducing agent. At the first stage, the optimal nonionic surfactant was determined for the stabilization of selenium nanoparticles. The obtained samples were studied by dynamic light scattering and acoustic and electroacoustic spectroscopy. It was found that nanoselenium samples stabilized with Tween 80 have the smallest radius (16 nm), and the zeta potential was 17.91 mV. Further, the obtained samples were examined using transmission electron microscopy. The analysis of the obtained micrographs showed that the selenium nanoparticles stabilized with Tween 80 have a spherical shape, and the radius lies in the range from 12 to 22 nm. At the final stage, we studied the effect of exposure time on the aggregative stability of selenium nanoparticles. The results obtained showed that after 5 weeks of exposure, aggregates were formed in the sample, and the average particle radius increased by 2.8 times from 16 to 45 nm Selenium nanoparticles, nonionic surfactants, Tween 80, average hydrodynamic radius, transmission electron microscopy

The work was supported by the Russian Science Foundation (grant no. 23-16-00120, https://rscf.ru/project/23-16-00120/). The study was carried out using the equipment of the North Caucasus Federal University Shared Use Center with financial support from the Ministry of Science and Higher Education of the Russian Federation (unique RF project identifier 2296.61321Х0029)

Please cite this article in English as:

Blinov A.V., Rehman Z.A., Gvozdenko A.A., et al. Synthesis and study of stabilization of selenium nanoparticles in the medium of water-soluble nonionic surfactants. Herald of the Bauman Moscow State Technical University, Series Natural Sciences, 2024, no. 2 (113), pp. 103--115 (in Russ.). EDN: LWCFBA

References

[1] Khurana A., Tekula S., Saifi M.A., et al. Therapeutic applications of selenium nanoparticles. Biomed. Pharmacother., 2019, vol. 111, pp. 802--812. DOI: https://doi.org/10.1016/j.biopha.2018.12.146

[2] Ferro C., Florindo H.F., Santos H.A. Selenium nanoparticles for biomedical applications: From development and characterization to therapeutics. Adv. Healthc. Mater., 2021, vol. 10, iss. 16, art. 2100598. DOI: https://doi.org/10.1002/adhm.202100598

[3] Gubarev A.S., Lezov A.A., Mikhailova M.E., et al. Ag(0) nanoparticles stabilized with poly(ethylene glycol)s modified with amino groups: formation and properties in solutions. Colloid J., 2019, vol. 81, no. 13, pp. 226--234. DOI: https://doi.org/10.1134/S1061933X19030062

[4] Bisht N., Phalswal P., Khanna P.K. Selenium nanoparticles: a review on synthesis and biomedical applications. Mater. Adv., 2022, no. 3, pp. 1415--1431. DOI: https://doi.org/10.1039/D1MA00639H

[5] Gudkov S.V., Shafeev G.A., Glinushkin A.P., et al. Production and use of selenium nanoparticles as fertilizers. ACS Omega, 2020, vol. 5, no. 28, pp. 17767--17774. DOI: https://doi.org/10.1021/acsomega.0c02448

[6] Kumar A., Prasad K.S. Role of nano-selenium in health and environment. J. Biotechnol., 2021, vol. 325, pp. 152--163. DOI: https://doi.org/10.1016/j.jbiotec.2020.11.004

[7] Kieliszek M. Selenium-fascinating microelement, properties and sources in food. Molecules, 2019, vol. 24, iss. 7, art. 1298. DOI: https://doi.org/10.3390/molecules24071298

[8] Chen N., Zhao C., Zhang T. Selenium transformation and selenium-rich foods. Food Biosci., 2021, vol. 40, art. 100875. DOI: https://doi.org/10.1016/j.fbio.2020.100875

[9] Gac P., Czerwinska K., Macek P., et al. The importance of selenium and zinc deficiency in cardiovascular disorders. Environ. Toxicol. Pharmacol., 2021, vol. 82, art. 103553. DOI: https://doi.org/10.1016/j.etap.2020.103553

[10] Skesters A., Kustovs D., Lece A., et al. Selenium, selenoprotein P, and oxidative stress levels in SARS-CoV-2 patients during illness and recovery. Inflammopharmacol., 2022, vol. 30, no. 2, pp. 499--503. DOI: https://doi.org/10.1007/s10787-022-00925-z

[11] Blinov A.V., Maglakelidze D.G., Rekhman Z.A., et al. Investigation of the effect of dispersion medium parameters on the aggregative stability of selenium nanoparticles stabilized with catamine AB. Micromachines, 2023, vol. 14, iss. 2, art. 433. DOI: https://doi.org/10.3390/mi14020433

[12] Siddiqui S.A., Blinov A.V., Serov A.V., et al. Effect of selenium nanoparticles on germination of Hordeum vulgare barley seeds. Coatings, 2021, vol. 11, iss. 7, art. 862. DOI: https://doi.org/10.3390/coatings11070862

[13] Pekarkova J., Gablech I., Fialova T., et al. Modifications of parylene by microstructures and selenium nanoparticles: evaluation of bacterial and mesenchymal stem cell viability. Front. Bioeng. Biotechnol., 2021, vol. 9, art. 782799. DOI: https://doi.org/10.3389/fbioe.2021.782799

[14] Blinov A.V., Nagdalian A.A., Siddiqui S.A., et al. Synthesis and characterization of selenium nanoparticles stabilized with cocamidopropyl betaine. Sc. Rep., 2022 vol. 12, art. 21975. DOI: https://doi.org/10.1038/s41598-022-25884-x

[15] Lesnichaya M.V., Aleksandrova G.P., Malysheva S.F., et al. Synthesis of selenium-containing humic nano-biocomposites from sodium bis(2-phenylethyl)phosphi-nodiselenoate. Russ. J. Gen. Chem., 2020, vol. 90, no. 1, pp. 123--128. DOI: https://doi.org/10.1134/S1070363220010193

[16] Valueva S.V., Borovikova L.N. Influence of the nature of a biologically active stabilizer on the spectral and dimensional characteristics of hybrid selenium-containing nanosystems. Zhurnal fizicheskoy khimii [Journal of Physical Chemistry], 2019, vol. 93, no. 1, pp. 113--118 (in Russ.). DOI: https://doi.org/10.1134/S0044453719010308

[17] Valueva S.V., Vylegzhanina M.E., Plyushchenko A.V. Atomic force microscopy and the optical characteristics of hybrid polymeric nanosystems based on silver and selenium nanoparticles. J. Surf. Investig., 2019, vol. 13, no. 4, pp. 586--593. DOI: https://doi.org/10.1134/S1027451019040177

[18] Boroumand S., Safari M., Shaabani E., et al. Selenium nanoparticles: synthesis, characterization and study of their cytotoxicity, antioxidant and antibacterial activity. Mater. Res. Express, 2019, vol. 6, no. 8, art. 0850d8. DOI: https://doi.org/10.1088/2053-1591/ab2558

[19] Gablech E., Fohlerova Z., Svec K., et al. Selenium nanoparticles with boron salt-based compound act synergistically against the brown-rot Serpula lacrymans. Int. Biodeterior. Biodegradation, 2022, vol. 169, art. 105377. DOI: https://doi.org/10.1016/j.ibiod.2022.105377

[20] Knepper T.P., Berna J.L. Surfactants: properties, production, and environmental aspects. Compr. Anal. Chem., 2003, vol. 40, pp. 1--49. DOI: https://doi.org/10.1016/S0166-526X(03)40004-4

[21] Salager J.-L., Anton R., Bullone J., et al. How to use the normalized hydrophilic-lipophilic deviation (HLDN) concept for the formulation of equilibrated and emulsified surfactant-oil-water systems for cosmetics and pharmaceutical products. Cosmetics, 2020, vol. 7, iss. 3, art. 57. DOI: https://doi.org/10.3390/cosmetics7030057

[22] Une V.R., Bondarde M.P., Some S. Formulation and development of water-based fragrance from patchouli essential oils using nonionic surfactant. Appl. Nanosci., 2022, vol. 12, no. 9, pp. 2117--2125. DOI: https://doi.org/10.1007/s13204-022-02489-4

[23] Arya S.S., Kaimal A.M., Chib M., et al. Novel, energy efficient and green cloud point extraction: technology and applications in food processing. J. Food Sci. Technol., 2019, vol. 56, no. 13, pp. 524--534. DOI: https://doi.org/10.1007/s13197-018-3546-7

[24] Nirmala M.J., Durai L., Rao K.A., et al. Ultrasonic nanoemulsification of Cuminum cyminum essential oil and its applications in medicine. Int. J. Nanomedicine, 2020, vol. 15, pp. 795--807. DOI: https://doi.org/10.2147/IJN.S230893