Alkaloids Electrochemical Multisensor Express Analysis in the Electronic Tongue Format

Abstract

The paper presents a method of multisensor inversion voltammetry to detect and identify the alkaloids macro quantity in a test sample. In contrast to the existing multisensor systems using a set of indicating electrodes, the proposed method envisages a line of sensors formed on the surface of a single planar three-electrode system at introducing in the background electrolyte a number of transition metal ions and forming complexes with the sample toxic substances of the sample. Effect of each organic substance on the electrochemical behavior of the multisensor test system is different; therefore, it becomes possible to use the electrolyte solution containing a set of cations of various metals as the test system. The developed method advantage lies in obtaining reliable results with low labor intensity and in high efficiency of the analysis. Taking into account specifics of the substances under identification, composition of the electrochemical test system was optimized, and information parameters characterizing the alkaloids presence in the test sample were identified. Successful application of the proposed method in analytical studies leads to its implementation in the electronic tongue format. Based on the results of the research conducted, a method of analysis is proposed that with high reliability makes it possible to detect and identify alkaloids both in the laboratory and in the out-of-laboratory conditions

Please cite this article in English as:

Petrenko E.M., Semenova V.A. Alkaloids electrochemical multisensor express analysis in the electronic tongue format. Herald of the Bauman Moscow State Technical University, Series Natural Sciences, 2022, no. 6 (105), pp. 144--156 (in Russ.). DOI: https://doi.org/10.18698/1812-3368-2022-6-144-156

References

[1] Simonov E.A., Makarov V.G. Ispolzovanie metodov kapelnogo analiza dlya obnaruzheniya narkoticheskikh sredstv vo vnelaboratornykh usloviyakh. V kn.: Kriminalistika: 21 vek [Use of drip analysis methods for the detection of narcotic drugs in out-of-laboratory conditions. In: Criminalistics: 21st century]. Moscow, EKTs MVD RF Publ., 2001, p. 3 (in Russ.).

[2] Chai X.-S., Dong C., Deng Y. In situ determination of bacterial growth by multiple headspace extraction gas chromatography. Anal. Chem., 2008, vol. 80, no. 20, pp. 7820--7825. DOI: https://doi.org/10.1021/ac801537x

[3] Kogan V.T., Antonov A.S., Lebedev D.S., et al. Direct mass-spectrometric measurement of methane and its volatile homologues in water. Tech. Phys., 2013, vol. 58, no. 3, pp. 439--446. DOI: https://doi.org/10.1134/S1063784213030146

[4] Ekman R., Silberring J., Westman-Brinkmalm A.M., et al. Mass spectrometry. Wiley, 2008.

[5] Lukovtsev V.P., Doronin A.N., Lukovtseva N.V., et al. Identification of alkaloids using the stripping voltammetry method. Russ. J. Electrochem., 2009, vol. 45, no. 7, pp. 810--812. DOI: https://doi.org/10.1134/S1023193509070167

[6] Budnikov G.K. Determination of substances trace amounts as a problem of modern analytical chemistry. Sorosovskiy obrazovatelnyy zhurnal, 2000, vol. 6, no. 3, pp. 45--51 (in Russ.).

[7] Doronin A.N., Kolesnichenko I.I., Tikhonova S.V., et al. The effect of papaverine on cadmium electrodeposition on glassy carbon electrode modified with mercury. Russ. J. Electrochem., 2012, vol. 48, no. 9, pp. 941--943. DOI: https://doi.org/10.1134/S1023193512080034

[8] Kolesnichenko I.I., Klyuev A.L., Ganshin V.M., et al. Express screening of biological objects using multisensory inversion voltammetry with pattern recognition. Prot. Met. Phys. Chem. Surf., 2014, vol. 50, no. 4, pp. 543--547. DOI: https://doi.org/10.1134/S2070205114040078

[9] Singh S. Sensors --- an effective approach for the detection of explosives. J. Hazard. Mater., 2007, vol. 144, iss. 1-2, pp. 15--28. DOI: https://doi.org/10.1016/j.jhazmat.2007.02.018

[10] Ganshin V.M., Fesenko A.V., Chebyshev A.V. From olfactory models to the "electronic nose". New features of parallel analytics. Spetsialnaya tekhnika, 1999, no. 1-2, pp. 2--11 (in Russ.).

[11] Vlasov Yu.G., Legin A.V., Rudnitskaya A.M. Electronic tongue: chemical sensor systems for analysis of aquatic media. Russ. J. Gen. Chem., 2008, vol. 78, no. 12, pp. 2532--2544. DOI: https://doi.org/10.1134/S1070363208120335

[12] Vlasov Yu.G., Ermolenko Yu.E., Legin A.V., et al. Chemical sensors and their systems. J. Anal. Chem., 2010, vol. 65, no. 9, pp. 880--898. DOI: https://doi.org/10.1134/S1061934810090029

[13] Raman B., Meier D.C., Evju J.K., et al. Designing and optimizing microsensor arrays for recognizing chemical hazards in complex environments. Sens. Actuators B Chem., 2009, vol. 137, iss. 2, pp. 617--629. DOI: https://doi.org/10.1016/j.snb.2008.11.053

[14] Feng L., Musto C.J., Kemling J.W., et al. A colorimenric sensor array for identification of toxic gases below permissible exposure limits. Chem. Commun., 2010, vol. 46, iss. 12, pp. 2037--2039. DOI: https://doi.org/10.1039/B926848K

[15] Shlefer G.L. Kompleksoobrazovanie v rastvorakh [Complexation in solutions]. Moscow, Leningrad, Khimiya Publ., 1964.